Christina Applegate discharged from hospital after nearly four-month hospital stay

Christina Applegate was reportedly discharged from the hospital nearly four months after she was admitted in late March.

The actress, who has been battling multiple sclerosissince 2021, is back home and doing well, an insider told TMZ Monday.

A rep for Applegate, 54, wasn’t immediately available to Page Six for comment.

Christina Applegate sits barefoot, cross-legged, next to her newly unveiled star on the Hollywood Walk of Fame.
Christina Applegate (seen above in 2022) was reportedly released from the hospital. AFP via Getty Images
Christina Applegate, masked, walking with a cane and wearing an
The actress (seen here in November 2024) is back home after nearly four months, TMZ reported Monday. VEGAN / BACKGRID

It remains unclear if the “Dead to Me” alum was hospitalized due to her autoimmune condition, which is a disease of the brain and spinal cord that “can cause numbness, weakness, trouble walking [and] vision changes,” per Mayo Clinic.

At the time, her rep refused to confirm her medical treatments, telling Page Six in a statement, “She’s had a long history of complicated medical conditions that she has been refreshingly open about.”

A few days later, Applegate addressed her health scare via Instagram, thanking fans for their “outpouring of love and well wishes.”

Christina Applegate attends the 28th Annual Critics Choice Awards at Fairmont Century Plaza on January 15, 2023 in Los Angeles.
An insider told the outlet that Applegate (seen here in 2023) was doing well. Getty Images for Critics Choice Association
Christina Applegate at a podium, wearing a dark red velvet suit and holding a cane, waving her left hand.
The “Dead to Me” star (seen here in January 2024) is battling multiple sclerosis. Getty Images

“Health issues are a constant for me, but I’m a strong chick and I’m getting stronger and better every day,” she wrote.

“I’m taking a moment to focus on my health, but I’ll be back with more to say soon enough.”

Applegate’s “Married … With Children” co-star David Faustino, who portrayed her on-screen brother, gave an updateon the actress amid her hospitalization in June.

 Christina Applegate arrives onstage during the 75th Emmy Awards at the Peacock Theatre at L.A. Live in Los Angeles on January 15, 2024.
However, it’s unclear if the autoimmune disease led to her hospitalization. (Seen here: Applegate in January 2024.) AFP via Getty Images
Black and white photo of Christina Applegate, a woman with long hair and a light shirt, hands in her pockets, looking at the camera.
Applegate (seen here in October) shared in February that she was confined to her bed. christinaapplegate/Instagram

“It’s been very hard for her, but she does keep her humor,” the actor told Us Weekly, referring to her MS battle as “a real blow.”

“She gets through this with some humor, and that’s kind of her way that she moves through it,” he continued. “I do a lot of visits with her. A lot of texting, a lot of checking in.”

Applegate portrayed Kelly while Faustino played the role of Bud Bundy in the long-standing TV show, which aired from 1987 to 1997.

The “Bad Moms” star has been open about his journey with MS, revealing on her “MeSsy” podcast in August 2025 how she was hospitalized with “so much pain” and “screaming” due to a kidney infection.

Christina Applegate and Sadie Grace LeNoble posing on the red carpet, both wearing black outfits.
At the time, Applegate explained that she still tried to get up to take her daughter, Sadie, to school (they’re seen here in February 2023). Variety via Getty Images
Christina Applegate in a black shirt, jeans, and rainbow suspenders, leaning against a door.
“I want to take her; it’s my favorite thing to do. It’s the only time we have together by ourselves,” she told People at the time. (Seen here: Applegate in January.) christinaapplegate/Instagram

Then, in February, Applegate revealed she was confined to her bed, though she still tried to be present for her and her husband Martyn LeNoble’s 15-year-old daughter, Sadie, taking her to school each day.

“I want to take her; it’s my favorite thing to do. It’s the only time we have together by ourselves,” she told People. “I tell myself, ‘Just get her there safely and get home so you can get back into bed.’ And that’s what I do.”

Additionally, the “Sweetest Thing” star has revealed how difficult her MS battle has been on Sadie after the latter admitted to missing who Applegate was before her diagnosis.